Wednesday, December 31, 2014

Embryo grades means nothing. PGS is the only way to determine karyotype

My clinic does not reveal the gender of our embryos, however after explaining to my RE why I needed to know should I have another miscarriage, he said yes he would contact Natera to find out the gender once I am pregnant.  The karyotyping after a miscarriage is not always a sure thing because of the maternal cell contamination. They don't do gender selection which is understandable. I agree that every embryo has a right to have a chance. He told me the grade of the abnormal embryo - AA! - female.  To me, this, proves that the grade or quality is not an effective way to choose an embryo. I said to him "so my other 2 miscarriages with AA embryos could have been chromosomal too?" and he answered "Yes possibly but it is unlikely that embryos produced from the eggs of a 26 year old donor would give 3 out of 6 abnormal embryos". He then added that he doesn't know what my problem is...

Monday, December 29, 2014

PGS results

Eric and I returned from our holidays in Barbados yesterday. Well this morning really, We arrived at midnight and they lost one of our luggage so we were there an extra hour filling out a missing baggage claim. Finally went to bed at 2 am! I had a voicemail from my nurse. The results from the embryos came back on 22nd December. We have 3 embryos with normal chromosomes and ONE had abnormal chromosomes (Monosomy 20). Hopefully this gives us our answer. That it was most probably a chromosome abnormality with the 2 DE miscarriages I had this year also. It's exactly what I have been praying for, that just one would be abnormal,  to let us know there could have been a chromosome problem. Now we still have 3 healthy frosties! If all 4 had been NORMAL though, we definitely would have had to wait and save up years for a gestational carrier.

Embryo       Grade       PGS result
#1                  AA           Abnormal
#2                  AB           Normal
#3                  AB           Normal
#4                  BB           Normal

I am sick with a bad cough from an infection in my throat and a rash on my hands. At first I thought it was sinusitus, but think otherwise after seeing the rash, I have an appointment with my GP tomorrow. Alot of people are suffering from mosquito transmitted diseases in Barbados at the moment. Like chikungunya and dengue fever . I don't get ill much, but I always seem to catch something when I travel.

Tuesday, December 2, 2014

miscarriage #6 - 6 weeks 1 day

I buried what would have become our baby in the plant we bought back from our honeymoon in Hawaii.  It may seem strange but I felt that I had to do something respectful. I feel this was most likely a blighted ovum. It was nothing like the natural miscarriage I had 5 years ago when I was almost 10 weeks and baby had stopped growing at 7 weeks. The pain was worse than kidney stones with vomiting for 5 hours and then passing out just as I passed the sac. I had none of that this time. I did pray that if this was a non-viable pregnancy to let it happen soon and not when we would be on vacation in 2 weeks. I have betas starting Friday to monitor hcg levels back down to zero.

I just got an email from my Egg donor nurse with consents for PGS Embryo biopsy. I wonder if the timing is not just a coincidence...

Monday, December 1, 2014

Beta #4

My Ob phoned today. I was sure she was going to tell me my numbers had gone down. However she said they were still rising and were at 931. When I sighed she said not to worry about the slow rising numbers and since the last beta was done at the hospital in a different lab, we should disregard that one and just calculate from beta on 24th which was 453. This is a doubling of  98 hours which is much lower than normal. From what I have read, seems to be a blighted ovum. I have never had one of those. I am praying it is not ectopic. However the doctor wasn't too concerned, She was happy I wasn't having any cramping which would be a bad sign and indicate ectopic. She said if I have any cramping to call immediately. She said to just wait until my ultrasound on the 9th December and do another beta then. I confessed to taking the Wobenzyme n. I told her that it had removed all the pain from my fingers and I felt much better on it.  Her response surprised me as most doctors do not believe in supplements. She said "Well that is good". She didn't tell me I should stop taking them. With George the betas slowed right down to doubling of 252 hours and we still saw a HB. So news could be worse.

Wednesday, November 26, 2014

Visit to the ER and Beta #3

Had to go to the ER for spotting to get a Rhogam shot. My beta was 780. U/s showed no gestational sac...Have to repeat quant beta in 2 days. Praying it's not ectopic. The doctor said the hcg  doesn't indicate ectopic, but it has slowed down to doubling at 70 hours. She said they don't normally see anything on u/s until betas are at least 1000. However my lab paperwork shows they could not rule out ectopic either since this is a PUL. So another beta for me on Friday. They also saw a small fibroid, so I am wondering if that is what is causing the spotting. Strange because on CD 10 my RE said my saline sonogram was flawless. He is the one who caught the first fibroid I had removed in 2010. He has an eagle eye so I know he would have seen it.

Tuesday, November 25, 2014

Beta #1 & 2

  So the nurse phoned this morning and said The Ob wanted to schedule a viability u/s in 2 weeks. I said "What? I haven't gotten any beta numbers yet!"  They had never phoned me with the 1st one from Friday so I was assuming the worst.  She said Beta #1 on Nov 21st was 183 and Beta #2 Nov 24th was 453! So doubling time of 50.5 hours. I have always had strong symptoms with all my failed pregnancies. Over 400 I should be feeling something other than sleepiness right? Maybe its the wobenzym masking symptoms like prednisolone does?  My viability u/s is 9th December. I am torn as to whether or not I should call my donor egg nurse and tell her. I still have some prednisolone here but 5 mg didn't work for the last pregnancy. Maybe I should just stick to Wobenzym. Idk. Ob's nurse said she will not prescribe it as she does not believe it has any positive effects. So much for being a high risk Ob.

Monday, November 24, 2014


This cheered me up! My new supplement SOUL by Rain (Essential fatty acids and anti-oxidants)finally arrived from CA! My childhood friend who also has struggled to have a baby told me a doula recommended this supplement. She said that it works similar to intralipids.  Since I can't get a doctor to prescribe intralipids. Giving this a try :)
Ingredients:black cumin seeds, black raspberry seeds, grape seed, D-Ribose.

Another Beta and still waiting...

Ob hasn't phoned me back with result from my 1st beta I had on the 21st. I had my second one drawn this morning.  It is sad that at my age doctors feel it must not be a viable pregnancy. I bet she is waiting to phone me tomorrow with the 2 betas so that she can tell me straight up that the numbers didn't double. *sigh* The thing is IF it is a viable pregnancy, then I need to switch to prednisolone. I already explained this to her nurse.  I cannot phone my ivf nurse because last year with both of my spontaneous pregnancies I phoned my RE's office and told them I was pregnant and I was so scared to miscarry again, could they have him phone me back and they said I would have to contact an OB. He didn't phoned me back either. The next time I saw him was when I had my hsg for donor egg. So when I got pregnant with George and Eric said the pregnancy looked like it was measuring behind like the one before. The RE said he had no record of that pregnancy. I answered" no because you never phoned me back."

here is my pee stick from yesterday:

Friday, November 21, 2014


Still waiting on biopsy and PGS of embryos to be done and I missed my period!! I am 43! Eric was away on a business trip and we only had Nookie once before he left (not even sure where in my cycle I was??) What are the chances of this happening? They say there is always a reason things happen right? I decided to test over the weekend because had red spotting on CD 23. (That was my uh-oh moment). I got a faint line on a FRER after a full 5 mins on CD 28. However my breasts stopped being sore the next day so thought it might be a chemical. Tested again yesterday and today and lines are getting darker. It is sad to say but I feel total and utter desperation with this pregnancy.  Gone are days of bursting with joy, racing heart, tears of joy. I feel sad for this little embryo. I don't think it has much of a chance in my evil uterus without steroid treatment. I phoned Ob and getting beta #1 this afternoon. Trying to stay zen and just breathe...

Nov 20th:

Nov 21st

Thursday, November 6, 2014

Wobenzym N

Yesterday I started a new supplement. I did quite a bit of research on it first.  I have also talked to a lady online who has had success after multiple losses. She said it works much like prednisone without the side effects. I figure I can take it until a month before my next FET and then switch to the prednisolone since I know my RE will roll his eyes at this supplement.

My nurse contacted me and said they would be doing the biopsy for PGS on our embryos next week.! Yay! Finally!

Thursday, October 30, 2014

Saline sono and mammogram

I had a saline sono yesterday to make sure I didn't have any adhesions from my 3rd d & c in July.  Thankfully, my doctor said my uterus looked great. He added with a smile "I must say, this is your best one so far". Then I had a clean bill after my mammogram in the afternoon. So, it was a good day. Now we wait for PGS.

Tuesday, September 30, 2014

Patience is a virtue

The biopsy on our embryos has not been done yet.  I probably should not have been so eager to order the blood test for Eric. I was in San Francisco when I made the appointment and the connection wasn't good and the lady must have only heard the "genetic screening" when I said "pre-genetic screening".  So that is where Eric's blood was sent. To Councyl. So from that,we found out that he is a carrier of Cystic Fibrosis. Our donor and I are both negative for that disease so it is not a concern for us since both parents need to contribute a gene for cystic fibrosis. However I read that a carrier of cysstic fibrosis often suffers with infertility, Kind of explains the 3 years it took to get a bfp.

Eric had to have a his blood drawn again. Our donor had hers drawn but results are still pending. Since we are going to be in Barbados for 2 weeks in December we have decided to wait until February?March for our next transfer. Depending on the PGS results of course.

I can't believe summer is over already and I missed out on many of the things I look forward to in the summertime.  Going through a 5th miscarriage and d & c was not how I envisioned it.  I was looking forward to Thanksgiving and Christmas being pregnant.  Each year those holidays become an even more painful reminder that infertility sucks big time!

Friday, August 8, 2014


August 1st my HCG levels were finally down to zero!  I talked with our Re last week and I insisted that we wanted to have the Natera 24 chromosome PGS. Our clinic uses the vitrification method of freezing so hopefully our embryos will be ok. Eric and I wanted to do PGS before the embryos were cryopreserved, but when I asked our RE he did not think it was necessary. He said that young women (our donor is 25) do not have aneuploid eggs. However, I have done some research and this is NOT true. Yes they have alot less than someone my age. However, when their ovaries are stimulated to produce 30 eggs, there is a lot more chance of aneuploidy. I read a lady's blog a couple months ago and her experience with PGS. She said that her best two AA blastocysts were the ones with aneuploidy and the two that were given a less desirable grade were the chromosomally normal ones.  I am praying that the PGS gives us some answers regarding my last 2 miscarriages. Hopefully by transferring a euploid blastocyst and doing the prednisolone and lovenox therapy that we will have our rainbow at last.

Wednesday, July 23, 2014

Maternal Cell Contamination

 I am so upset!  As if we have not had enough bad luck already, the doctor said there was Maternal cell contamination of the Karyotype results on the miscarriage.  So we are left with no answers whatsoever!! Normal female XX which the doctor said was probably from my cells because it matched my blood :( This is the worst possible outcome. Now we don't know whether it was the NK cells in my uterus that caused the miscarriage or if there was a chromosome issue :( No answers. Where do we go from here? I feel so empty, like I went through another miscarriage and there is no evidence that this pregnancy ever even happened and that George ever existed :(

Sunday, July 13, 2014

D & C

I had a d & c July 11th. hopefully we get some answers from the karyotyping.  I am praying it is a chromosome issue and that it was not my Nk cells in my body that attacked a healthy baby. :(
I was looking forward to being pregnant on my birthday July 20th. Everything happens for a reason everyone keeps telling me. All I know is I need to be strong because I have a wonderful husband who is good to me and losing all these babies is affecting him just as much as me. I am grateful for having him in my life and everything we have been through has brought us even closer together.

Monday, July 7, 2014

3rd ultrasound- 8 weeks 4 days- No heartbeat :(

RIP George. You will be in our hearts always. We love you and will miss you...
(last CRL measurement was 1.3 cm (13 mm) 7 weeks 6 days)

Saturday, June 28, 2014

2nd ultrasound

Yesterday's ultrasound (June 27th) was bittersweet. We heard our baby's heartbeat. :) Yet the doctor measured me at only 6 weeks 3 days when I should be 7 weeks. I know in my past pregnancies this has meant doom. Especially since the heart rate was 109 and last week was 108 so has not increased. According to this site this is considered moderately low.

I will continue to pray for our baby. When we have faith there can be no fear. I have another sonogram in 10 days. Was supposed to be in one week but it is 4th July weekend so I have to wait till 7th July. Patience really is a virtue!

I did notice something interesting about the sonogram. Last week the time that was registered on the sonogram was 11:11am! And this week was 1:11!  I often see 11:11 or 1:11 when I look at the clock and I have read that this means an angel or loved one that has passed or your guardian angel is trying to communicate with us.  I started seeing this after Paula, my sister in law died. So I believe she is looking out for George. God as usual, I am handing everything over to you.

Friday, June 20, 2014

First ultrasound and Heartbeat!

I am in shock! First ultrasound today. Eric and I saw our baby and a heartbeat!! Measuring right on track at 6 weeks 1 day! The nurse made me crazy with slow rising beta numbers and possible ectopic for about a week. I asked the doctor about it and he said the ultrasound is all that matters and everything looks perfect. The nurse just phoned to say I should make an appointment with an OB. I asked "So what about the slow rising beta numbers?" She said "Oh that could have been anything". I do not have any pregnancy symptoms other than sore breasts but I am still pregnant! Praise the Lord!

Thursday, June 19, 2014

6 weeks

I have zero symptoms other than period like cramps when I first wake up and frequent urination.  The very sore breasts are from the daily Progesterone in oil injections. I still have the extreme hunger and fatigue. Usually at 6 weeks the morning sickness is at full force.  Well maybe that means this is a male since I had lots of morning sickness with the female we lost a year ago. First ultrasound tomorrow. I am praying constantly. I am gardening to pass the time and keep my mind off everything. Those darn rabbits won't stop digging up my radishes and chewing the leaves off my cucumber plants! I will need to get more fencing like I have around the strawberry plants......

Monday, June 16, 2014

4th Beta (5 weeks 4 days)

My beta is 3463 . It has only doubled after 252 hours :(   I asked the nurse what this could mean. She said they want to check to see if the pregnancy in in the correct place. In other words they are worried about an ectopic pregnancy. Either that or the baby stopped progressing. So Friday, June 20th is my 1st sonogram. Four pregnancies during a span of 16 months. Last year 20th June I also got bad news with our angel girl. I was 8 weeks and that was the day they could no longer find her heartbeat :( It is so hard to not be negative when I have had 4 miscarriages. I know that slow rising betas a not a good sign. Yet I refuse to believe that God would let us come this far and not have success.
  • 1st Beta 06-09-14 - 13dp5dt-1137! 
    2nd Beta 06-11-14 - 15dp5dt-1923- 64 hour doubling (normal)
    3rd Beta 06-13-14 - 17dp5dt-2842- 85 hour doubling (Lower than normal)
  • 4th Beta 06-16-14 - 20dp5dt-3463-252 hours doubling (Much lower than normal)
  • :(

Friday, June 13, 2014

3rd Beta

My nurse took a long time to phone with my beta. I think it is because my numbers are rising even slower. :(  HCG only increased by 48% to 2842. The range is between 72-96 hours. SInce mine is  doubling after 83 hours, I am on the low end of that range. She said not to lose hope because my numbers started out high. I know if that was the OB I had last year she would have said this is not looking like a viable pregnancy. The nurse said that we would find out more on sonogram next Friday.  I appreciate her being encouraging. I asked for another beta because a week is a long time to wait! So Monday I have one final beta. Strangely enough I don't feel scared or upset. Maybe my body knows everything will be ok? Intuition? I hope! The crawling has resumed in my ankle and gives me a bit of reassurance. Like Eric said maybe I just needed some acupuncture to get the circulation going again.

I had acupuncture this morning. It is supposed to help with reducing NK killer cells. I am still praying for a miracle.

Thursday, June 12, 2014

2nd Beta

My 2nd beta  Wednesday 11th was 1923. The nurse said it was rising nicely. When I asked "Shouldn’t it have doubled?" She said no, they are looking for a 60 % rise and mine rose by 69 %. I think that they prefer it to double every 48 hours but the nurses there are so encouraging. I had some period-like cramping which worried me because I have not had any fluttering or stretching at all so this does not seem good.

I have to have another beta on Friday 13th. So much for my nurse saying I wouldn’t have to have as many betas if I waited a week after I got my first positive.  With the pregnancy I had last May/June the OB only made me have 2 betas. I remember her saying that all was well because the numbers were doubling every 48 hours.
I requested the 3rd myself because I was being cautious. Trying to think positive... at least it went UP and not down. 

The online hcg calculator says:
Under 1200 mIU/ml they look for doubling of 31-72 hours.
Then between 1200 to 6000 mIU/ml 72-96 hours. 
Mine is doubling after 63 hours so I am still in range.
I wish I had insisted to have my first beta last week. Then I would have at least known if it was doubling early on.. Seems that after 1200 they do not always double. I would not have had to wait 2 days waiting and wondering..The graph shows that my first beta was even higher than "maximum" so I can't help but think maybe our embryo split in 2 and only one implanted properly? Vanishing twin. I know it is common when 2 embryos are transferred. The chance of one embryo splitting are slim but still possible with a FET.

Neither Eric nor I got much sleep last night! I woke up at 2 am and was very hormonal and emotional. 
I didn't feel pregnant anymore because the crawling I get in my ankle every pregnancy has stopped. :(

I have a 7:30 am appoint for bloodwork again tomorrow and then acupuncture. Eric's shoulder is still hurting so we will both go for acupuncture afterwards.

Monday, June 9, 2014

1st Beta

My 1st Beta is 1137!  My nurse's exact words "You have a very pregnant beta of 1137!!"
This is my first successful IVF cycle! (After 3 BFN's in 2011, 2012 and a chemical pregnancy in February this year) Praise Jesus!  Last May at this stage of my natural pregnancy I had a beta of 244 so I am producing alot more HCG with this pregnancy. Here is my HPT from June 7th (11dp5dt) The test line is even darker than the control :)  Maybe IVF pregnancies implant sooner than spontaneous ones? Anyway, my due date is 11th February! Two days before Eric's birthday! Second beta is on the 11th June :)

Thursday, June 5, 2014

9 days past a 5 day transfer

I am 4 weeks today! The test line is just as dark as control line on hpt.Praise Jesus! I am going to acupuncture tomorrow to help relax me. I still have 4 days to go till my beta June 9th. I bought some cheap dollar store tests just in case I feel compelled to poas! lol

Monday, June 2, 2014


Isn't it amazing that even when you've yet to have a viable pregnancy...when all of your pregnancies have ended in miscarriage...those two lines send your head and heart right off 

Isn't it amazing that even when you've yet to have a viable pregnancy...When all of your pregnancies have ended in miscarriage...Those two pink lines start your heart pitter pattering and your tummy feeling like butterflies are fluttering around in there! I am 6dp5dt.  I would not even call this a quinter. The line is definately there! I still have a whole week to wait for my beta!

Eric's does not like Mondays. Who does? So I thought if only I got a positive today, it would help start his week off on the right foot...And I did :) I usually hold off longer to test but I had some strong implantation cramps two days ago so I thought why not? lol

Thank-you Lord! Please protect our baby from those evil cytokines and Antinuclear Antibodies in my body. It is all in your hands now!

Thursday, May 29, 2014

Frozen embryo transfer -27th May

Tuesday the 27th May was my Embryo transfer. I had to cancel my acupuncture appointment because they scheduled me for 11:30 and it over a 2 hour drive to get there. However I could have gone to acupuncture because they bumped 2 people ahead of me. I had a full bladder from 10-12:15. Not fun. I think the 2 people they transferred before me had emergency transfers. That happened to me in 2012. They bumped me ahead of someone else . My transfer was suppose to be in the afternoon that time and they said I needed to come right away at 8am. Anyway I did not pee on the doctor so all is good! :)

My RE has agreed to let me take prednisolone and aspirin, for elevated antinuclear antibodies. I also have elevated Natural killer cells, which I asked by last OB to order from by Reprosource. but he would not order the test for me or interpret the results. It clearly said on the lab results HIGH next to NK cells.  So I haven't been able to get a prescription for intralipids. This seems to be the magic ingreidient for most ladies with cytokines who's blogs I have been follwoing :( Hopefully the prednisolone and baby aspirin therapy will be enough to keep those ANA and cytokines under control! I also take extra strength Krill oil which has Phospholipids. Praying for our rainbow baby! Eric has been calling our embryo "George" from the time he saw the embryo photo. He said he felt it would be good to give the baby a temporary name instead of referring to him /her as the embryo. He is so cute. George was his paternal grandfather. It's also his middle name. He joked that if it's a boy we can nickname him Boy George LOL (He knows I loved Culture club when I was a teen). If it's a girl, maybe Georgia? lol

Wednesday, February 26, 2014

Giving IVF another try

Embryo retrieval day!! Huge ice storm so Eric and I drove up the night before. Good thing we drove up there the night before.. half an inch of ice and Chesterbrook was hit especially hard. No power. Our hotel room was one of those fantasy rooms. Which was all the Radisson had available. There was a jacussi near the bed, mirrors on the ceiling above the bed and on the walls! Lol Eric thought it was tacky. I couldn’t stop giggling. I could see he was didn’t like it and I wanted him to be comfortable so I asked to be changed to standard room. I told him I had visions of chains and whips . Who knows what goes on in those fantasy rooms.hehe. We couldnt use the jacussi anyway..Not good for Eric’s swimmers. We also did not like that it had NO windows. Weird! LOL
The bathroom was nicer and bigger in the standard and was the same price. Our room had 2 queen sized beds in it so we just slept in the one BED. Eric liked it because it was a sleep number bed. That night he had a dream about Paula. I asked what she said. He got a little teary eyed when he said that he asked her if she was here and she replied “Yes I am”. So her spirit is watching over our embryos in PA. J
My brother in law's girlfriend phoned and she said there is no power as of this morning so we made our way back home to turn the generator home so we could save our fish aquariums. They need to be kept at 84 F especially the babies. I Have been busy trying to get the temperature of the fish tank back up to 84.

Day 1- We got 7 mature eggs. The other 3 were not mature. 30 eggs split between us and 2 other couples. That is pretty darn good! The best news is that All 7 Eggs were fertilized!! We are so ecstatic! Eric’s sperm did awesome!
Thank God for the generator or all our fish would have died! They are all ok even the 2 week old fry. I did huge water changes in all tanks since they had no filtration for several hours till we arrived home.

Day 2- Six 4-cell, one 5-cell. In the past we have never gone past day 3 but these ones are looking wonderful and I am hopeful. My nurse seemed confident I will have a day 5 transfer and booked the ET for Monday at 1:20 pm. We were without power till tonight. Had the generator running for 2 days.
Day 3- Seven 8 cell embryos):)) !! woohoo! That is exactly where they should be. Thank-you Lord!
Angelfish spawned again!! Third time in 5 weeks! That has to be a god sign! I believe that fish not only bring good luck but all this egg laying must be a sign of fertility in our home :)

Embryo transfer day!!Day 5- Day started pretty early with Eric receiving phone calls at 2:30 and 4:30 am!! Not fair since he was on call all last week. Found out they forgot to switch lines for the on-call guy. Poor Eric hardly got any sleep and I didn’t either. 2 ½ drive to drive to PA again.  On our way there RE phoned and said our embryos were excellent!!:
1 Early Blastocyst
2 Full Blastocysts
3 Expanded Blastocysts
1 (Grade AA)-Hatching Blastocyst – this is the one they transferred J

I asked the clinic if it we could give our donor an anonymous gift. I had a bracelet made from beautiful stones for her. I wrapped it in a red and white box and gift bag for Valentine's day with a note that said "We appreciate you so much!!" I hope she likes it. :)
We ate lunch at Pei Wei Asian diner. I had some hot food. Spicy shrimp J

Here is our perfect Grade AA embryo and God willing, yfuture baby:

We are having a huge snowstorm for Eric's birthday so pretty much snowed in and Eric has all this snow to shovel. Poor guy. We have 5 frosties. The 6th that didn't make it to freezing was probably the early blastocyst that was a bit slower than the others.
We got 2 feet of snow. So tired of winter! 5 dp5dt- did a frer hpt and saw a very faint line but Eric said it's just a waterline. Probably too early..I will hold off for 3 days if I can.
BFP!! Light second line on an early Answer hpt! Hoping this is our rainbow baby but not letting myself get too excited yet...

I've been getting BFP's every day but line isn't getting darker :( Digital said "PREGNANT 1-2 weeks" but it should be saying 2-3 weeks since. I am 4 weeks 2 days today. I read some posts that the weeks estimator is not always accurate so trying to stay calm, but can't help worrying...

BFN...Rainbow has slipped away again :( 
Beta is 3 and since less than 5. means Negative.I had what the doctor called a chemical pregnancy. :( This is my 4th loss in 4 years :(  I had a long discussion with my fertility doctor. I asked him if he would consider intralipids. He said their practice didn't do it but he would ask the other doctors. Of course they said NO. He said FET should be better. I still believe my immune system is attacking the embryos. I will ask my kind OB from last year if she will order the NK test for me from a lab called Reprosource in MA.